Head of Manufacturing Science & Technology

Job Description

Juno Therapeutics is a clinical-stage company that brings together three of the world’s leading cancer centers – Fred Hutchinson Cancer Research Center, Memorial Sloan-Kettering Cancer Center and Seattle Children’s Research Institute – in unique partnership to advance a broad pipeline of breakthrough immunotherapies. Juno will build on the foundation of novel immunotherapies to develop two distinct and complementary platforms – chimeric antigen receptors (CARs) and T-cell receptors (TCRs). To learn more, visit http://ift.tt/1HTDmyr.

Job Summary:
This position has primary responsibility for the JuMP site’s MSAT department. The position is responsible for technology transfers, manufacturing support (investigations, change controls, CAPAs, process capability/capacity/efficiency/quality improvements) and equipment/process validation. Also, responsible for providing employee guidance; development and coaching to ensure the teams are aligned to the site strategy and are supporting the site to deliver on our current contracts and business pursuits. As a member of the site leadership team, advises on manufacturing-related issues, initiatives and strategy for continuous improve of site manufacturing performance and culture. Represents the MSAT organization during customer/manufacturing network meetings, audits and regulatory inspections.

Primary Responsibilities:

• Performs all functions associated with leading the MSAT organization. This includes a focus on safety, resource planning, oversight of the work deliverables, oversight of group budgetary performance, oversight of the team’s process performance metrics, providing guidance and advice on Juno’s policy and procedures, promoting cross department interactions, mediating conflicts, providing manufacturing and science technical input, customer/network/regulatory interaction, providing guidance on company/site strategy, prioritizing work and assisting in establishing long term group direction and objectives.
• Coaching and development of MSAT Team
• Provides direct coaching, mentoring and development to each member of the MSAT management team both in execution of their group responsibilities and in their own personal development. Develops and coaches direct reports for future leadership roles. In addition, provide coaching and mentoring to every member of the MSAT organization for their personal and professional development
• Program project interaction
• Engage with program managers to ensure projects are planned and executed appropriately in order to deliver to, and meet the needs of our customers and the business. Provide JuMP input to technical development early in the process to ensure facility/operational considerations are factored into process decisions.
• Engage and Communicate with Site Leadership Team:
• Participate in site strategy decisions as a part of the site leadership team for JuMP. As a member of the site leadership team, lead cross-functionally with management, support departments, and customers to achieve site vision and strategy. Create a high-performance team that emphasizes strengths-based execution, accountability, open communication, people development and continuous improvement.
• Perform other duties as assigned.

QUALIFICATIONS AND EDUCATION REQUIREMENTS

• Bachelor of Science degree in Biological Sciences or Biomedical/Chemical Engineering.
• Preferred: Masters in Science or Engineering or PhD.
• Minimally 15+ years of biotech, cell therapy, pharmaceutical or medical device industry experience in process development, process scale up/manufacturing and process validation. Experience with commercial scale manufacturing support for mammalian cell culture, aseptic final product filling/kitting/labeling, liquid media manufacturing (vials, bags, bottles) and/or analytical reagent (e.g. endotoxin detection assay) manufacture, current Good Manufacturing Practices, US / EU regulations, and supervision.
• In depth knowledge of large scale biologic, pharmaceutical or medical device manufacturing, current Good Manufacturing Practices and US/EU regulations and intermediate knowledge of statistical data analysis. Knowledge should include a combination of cell biology, cell culture, and aseptic processing technologies and include small scale (laboratory) experience.

Our headquarters, situated in the bustling South Lake Union district of Seattle, sits among some of the most visible organizations in the world. Seattle offers award-winning restaurants, a vibrant, hip music scene and spectacular views of water and mountains. Within an hour’s drive of Seattle, you can be fishing, skiing, hiking or tasting world-class Washington wines.

THINK BIG. BE BRAVE. DELIVER.

Original job postingSubmit Resume

Let's block ads! (Why?)